ASSESSMENT OF EXOGENOUS AND ENDOGENOUS FACTORS ON THE FORMATION OF POST-TERM PREGNANCY

Abstract

Post-term pregnancy remains a significant problem in obstetrics due to its association with adverse perinatal outcomes. The aim of this study was to substantiate the pathogenetic influence of internal and external environmental factors on the development of post-term pregnancy. A comprehensive assessment of clinical and anamnestic data, environmental factors, hormonal status, and fetoplacental function was performed. Preliminary results demonstrated that post-term pregnancy is associated with endocrine imbalance, elevated stress-related hormone levels, unfavorable socio-environmental conditions, and impaired uteroplacental blood flow. These findings confirm the multifactorial nature of post-term pregnancy pathogenesis and highlight the need for personalized preventive strategies.