THE IMPORTANCE OF IL-6 CYTOKINE IN ORAL FLUID IN ORAL MUCOSITIS IN PATIENTS WITH CERVICAL CANCER

Authors

  • Jabborova Feruza Uzokovna Jabborova Feruza Uzokovna Author
  • Elova Hanifa Rakhmat Kizi Elova Hanifa Rakhmat Kizi Author

Abstract

Oral mucositis is a common complication of chemotherapy and radiation therapy, characterized by inflammation of the oral mucosa, pain, and a deterioration in patients' quality of life. Its development may lead to dose reduction or interruption of anticancer treatment.

In patients with cervical cancer receiving chemotherapy or combination therapy, the risk of inflammatory complications remains high, necessitating the search for early diagnostic markers.

Oral fluid cytokine profiling is considered a promising noninvasive method for assessing inflammation. Mucositis is associated with increased levels of proinflammatory cytokines, including IL-6, reflecting the activity of the pathological process. However, data on cytokine dynamics in this patient population are limited.

Author Biographies

  • Jabborova Feruza Uzokovna, Jabborova Feruza Uzokovna

    Associate Professor, Department of Therapeutic Dentistry, Bukhara State Medical Institute,

    Bukhara, Republic of Uzbekistan, PhD in Medicine;

  • Elova Hanifa Rakhmat Kizi, Elova Hanifa Rakhmat Kizi

    Third-Year Basic Doctoral Student,

    Department of Therapeutic Dentistry;

    Bukhara State Medical Institute, Bukhara,

    Republic of Uzbekistan

References

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Published

2026-04-29