EFFICACY OF LOCAL ADMINISTRATION OF TRAUMEEL S IN STIMULATING REPARATIVE OSTEOGENESIS IN PATIENTS WITH COMBINED FACIAL TRAUMA

Abstract

Reparative osteogenesis following fractures of the facial skeleton is a complex, multistage process that depends on adequate vascularization, mineral supply, and a balanced local inflammatory response. In combined facial trauma it is frequently compromised by extensive soft-tissue damage, infection risk due to communication between the fracture line and the oral cavity, and the systemic stress response to multiple injuries [1, 2]. Conventional treatment — surgical reduction, immobilization, and osteosynthesis combined with standard medication — does not specifically target the biochemical mechanisms of bone remodeling, which has led to growing interest in adjunctive agents capable of modulating local inflammation while promoting osteogenic activity [3].