Authors
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Ismailov Saydimurad Ibragimovich
Ismailov Saydimurad Ibragimovich
Author
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Zufarov Mirjamol Mirumarovich
Zufarov Mirjamol Mirumarovich
Author
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Sharapov Nodir Utkirovich
Sharapov Nodir Utkirovich
Author
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Makhmudov Kodir Oltinboevich
Makhmudov Kodir Oltinboevich
Author
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Abdullaeva Mokhima Abdullaevna
Abdullaeva Mokhima Abdullaevna
Author
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Mardonov Jamshid Normurotovich
Mardonov Jamshid Normurotovich
Author
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Mirzaev Xondamir Alisher ogli
Mirzaev Xondamir Alisher ogli
Author
Keywords:
ischemic heart disease, comorbidity, coronary calcium score index, coronary artery stenting and coronary artery bypass grafting.
Abstract
Ischemic heart disease (IHD) in women is characterized by specific features of pathophysiology, clinical course, and outcomes, which requires a differentiated approach to the selection of surgical treatment methods. The aim of the study was to develop a prognostic model for selecting a revascularization method (coronary artery stenting and aortocoronary bypass surgery) in women with IHD based on an analysis of comorbidities and clinical and instrumental data.
A retrospective study was conducted on 302 female patients with IHD. Analysis was performed of body mass index (BMI), coronary calcium score (CCIS), echocardiography, and spirometry data. It was found that overweight is associated with a higher likelihood of stenting (OR = 2.48; 95% CI 1.28–4.81), whereas obesity does not have a statistically significant effect. The most significant predictor of treatment choice is the CCS (χ² = 96.47; p < 0.001): with a CCI score of 0, the probability of stenting increases nearly 9-fold (OR = 8.80; 95% CI 4.42–17.51), whereas with a CCI score > 400, aortocoronary bypass surgery is predominantly performed.
The data obtained indicate the key role of coronary calcification and comorbid factors in the choice of revascularization strategy. The necessity of a multidisciplinary approach with mandatory assessment of CCI and the functional status of the respiratory system when planning surgical treatment of IHD in women is substantiated.
Author Biographies
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Ismailov Saydimurad Ibragimovich, Ismailov Saydimurad Ibragimovich
1Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov, Tashkent, Republic of Uzbekistan
2Tashkent State Medical University, Tashkent, Republic of Uzbekistan
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Zufarov Mirjamol Mirumarovich, Zufarov Mirjamol Mirumarovich
Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov, Tashkent, Republic of Uzbekistan
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Sharapov Nodir Utkirovich, Sharapov Nodir Utkirovich
Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov, Tashkent, Republic of Uzbekistan
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Makhmudov Kodir Oltinboevich, Makhmudov Kodir Oltinboevich
1Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov, Tashkent, Republic of Uzbekistan
2Tashkent State Medical University, Tashkent, Republic of Uzbekistan
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Abdullaeva Mokhima Abdullaevna, Abdullaeva Mokhima Abdullaevna
PhD
1Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov, Tashkent, Republic of Uzbekistan
2Tashkent State Medical University, Tashkent, Republic of Uzbekistan
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Mardonov Jamshid Normurotovich, Mardonov Jamshid Normurotovich
1Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov, Tashkent, Republic of Uzbekistan
2Tashkent State Medical University, Tashkent, Republic of Uzbekistan
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Mirzaev Xondamir Alisher ogli, Mirzaev Xondamir Alisher ogli
1Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov, Tashkent, Republic of Uzbekistan
2Tashkent State Medical University, Tashkent, Republic of Uzbekistan