A RISK-ADAPTED STRATEGY FOR PREVENTION OF RECURRENT ABDOMINAL ADHESIONS BASED ON IMMUNOLOGICAL PROFILING AND MINIMALLY INVASIVE SURGERY

Abstract

Abdominal adhesive disease remains one of the most significant unresolved problems in modern abdominal surgery. According to large European cohort studies, postoperative adhesions develop in 60–90% of patients after abdominal interventions, and up to 30–40% of all cases of intestinal obstruction are directly associated with adhesive processes. In the European Union alone, adhesive intestinal obstruction accounts for tens of thousands of hospital admissions annually, creating a substantial economic burden on healthcare systems.