CLINICAL SIGNIFICANCE OF IMMUNITY INDUCED BY THE HEPATITIS B VACCINE

Abstract

Viral hepatitis B is a chronic, sometimes acute, infectious disease caused by the hepatitis virus, characterized by various clinical manifestations (from mild to severe, fatal forms), often leaving serious complications, and is widespread among the population. The virus has a complex structure, consisting of two parts: the outer shell contains a superficial antigen HBcAg, and the inner core contains double-stranded DNK, the DNK polymerase enzyme, and HBcAg. Detection of antigens and antibodies of the hepatitis B virus has not only diagnostic, but also prognostic significance.