VILLOUS ARCHITECTURE AND MATURATION ABNORMALITIES OF THE PLACENTA IN PREGNANT WOMEN WITH CARDIAC DEFECTS: A HISTOPATHOLOGICAL ASSESSMENT

Authors

  • Isroilova Gulsanam Mukhtorjon kizi Isroilova Gulsanam Mukhtorjon kizi Author

Keywords:

cardiac defects in pregnancy, placental histopathology, villous maturation defect, maternal vascular malperfusion, terminal villous branching, syncytiotrophoblast, placental morphology, uteroplacental insufficiency, fetoplacental circulation, angiogenic imbalance

Abstract

This study examines characteristic villous architectural and maturation abnormalities of the placenta in pregnant women with cardiac defects. Systematic histopathological analysis reveals delayed villous maturation, increased maternal vascular malperfusion lesions, and reduced terminal villous branching as the primary morphological substrate of placental dysfunction in this high-risk obstetric population.

Author Biography

  • Isroilova Gulsanam Mukhtorjon kizi, Isroilova Gulsanam Mukhtorjon kizi

    Assistant, Department of Obstetrics and Gynecolog

    Fergana Public Health Medical Institute

     

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Published

2026-05-06