PATHOGENETIC MECHANISMS OF METABOLIC ADAPTATION PROCESSES IN LOW BIRTH WEIGHT INFANTS

Authors

  • Kalandarova Matlyuba Khodjiakbarovna Kalandarova Matlyuba Khodjiakbarovna Author

Keywords:

intrauterine malnutrition, metabolic programming, insulin resistance, leptin, adiponectin, epigenetic modification, glucose homeostasis, lipolysis, postnatal adaptation, catabolic state.

Abstract

This research provides comprehensive analysis of the pathogenetic mechanisms underlying postnatal metabolic adaptation processes in low birth weight infants. The study examines intrauterine malnutrition effects on the fetus, epigenetic programming, insulin resistance development, disruption of lipid and carbohydrate metabolism, hormonal dysregulation, and prognostic criteria for long-term metabolic outcomes. The findings establish a foundation for developing targeted nutritional support strategies during the neonatal period.

Author Biography

  • Kalandarova Matlyuba Khodjiakbarovna, Kalandarova Matlyuba Khodjiakbarovna

    Assistant of the Department of Traditional Medicine and Pharmacology

    Fergana Medical Institute of Public Health

References

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Published

2025-12-31

Issue

Vol. 2 No. 1 (2025): GLOBAL TRENDS IN SCIENCE AND INNOVATION

Section

Articles