THE ROLE OF MICROBIOME MODULATION IN BARRIER RESTORATION THERAPY FOR ATOPIC DERMATITIS: A CLINICAL ASSESSMENT

Authors

  • Ashurov Dilshod Davlatovich Ashurov Dilshod Davlatovich Author

Keywords:

cutaneous microbiome, Staphylococcus aureus colonization, dysbiosis, antimicrobial peptides, defensins, probiotics, metagenomic sequencing, tight junction proteins, microbiome-targeted therapy, epidermal barrier.

Abstract

This study investigates the contribution of cutaneous microbiome dysbiosis to epidermal barrier failure in atopic dermatitis and evaluates the clinical efficacy of microbiome-targeted adjunctive therapies. Through metagenomic sequencing and barrier function analysis, the research demonstrates that restoration of microbial diversity significantly augments conventional barrier-directed treatment outcomes and reduces disease recurrence rates.

Author Biography

  • Ashurov Dilshod Davlatovich, Ashurov Dilshod Davlatovich

    Fergana Medical Institute of Public Health

    Senior teacher of the Department of Dermatovenereology and Allergology

References

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Published

2026-05-19

Issue

Vol. 6 No. 2 (2026): SYMPOSIUM ON ADVANCED STUDIES AND FUTURE DIRECTIONS

Section

Articles