ANGIOGENIC BIOMARKER PROFILE AND VASCULAR MORPHOLOGY OF THE PLACENTA IN PREGNANCIES COMPLICATED BY MATERNAL CARDIAC DEFECTS

Authors

  • Isroilova Gulsanam Muxtorjon qizi Isroilova Gulsanam Muxtorjon qizi Author

Keywords:

cardiac defects in pregnancy, placental growth factor, soluble fms-like tyrosine kinase 1, fetoplacental vascular morphology, angiogenic imbalance, umbilical artery Doppler, placental microstructure, villous capillary density, syncytiotrophoblast stress, placental gene expression.

Abstract

This thesis characterizes the angiogenic biomarker profile and vascular morphology of the placenta in pregnant women with cardiac defects. Reduced placental growth factor expression, elevated antiangiogenic mediators, and quantifiable fetoplacental vascular rarefaction are identified as the molecular and structural determinants of placental dysfunction in this population.

Author Biography

  • Isroilova Gulsanam Muxtorjon qizi, Isroilova Gulsanam Muxtorjon qizi

    Assistant, Department of Obstetrics and Gynecology

    Fergana Public Health Medical Institute

     

References

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Published

2026-05-19

Issue

Vol. 6 No. 2 (2026): SYMPOSIUM ON ADVANCED STUDIES AND FUTURE DIRECTIONS

Section

Articles